gamma Actin (ACTG1) Rabbit Polyclonal Antibody

CAT#: TA324133

Anti-ACTG1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human liver cancer tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 4-379 amino acids of human actin, gamma 1
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42 kDa
• Gene Name: actin gamma 1
• Database Link:
  NP_001186883
  Entrez Gene 11465 MouseEntrez Gene 287876 RatEntrez Gene 71 Human
  UniProt ID P63261
• Background: Actins are highly conserved proteins that are involved in various types of cell motility; and maintenance of the cytoskeleton. In vertebrates; three main groups of actin isoforms; alpha; beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton; and as mediators of internal cell motility. Actin; gamma 1; encoded by this gene; is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26; a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.
• Synonyms: ACT; ACTG; BRWS2; DFNA20; DFNA26; HEL-176

Reference Data

• Protein Pathways: Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Tight junction, Vibrio cholerae infection, Viral myocarditis