AKR1A1 Rabbit Polyclonal Antibody

CAT#: TA324137

Anti-AKR1A1 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human liver cancer tissue, hela cells and human fetal kidney tissue
  IHC: 25-100
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm, Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 312-324 amino acids of human aldo-keto reductase family 1, member A1 (aldehyde reductase)
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 37 kDa
• Gene Name: aldo-keto reductase family 1, member A1 (aldehyde reductase)
• Database Link:
  NP_001189342
  Entrez Gene 58810 MouseEntrez Gene 78959 RatEntrez Gene 10327 Human
  UniProt ID P14550
• Background: This gene encodes a member of the aldo/keto reductase superfamily; which consists of more than 40 known enzymes and proteins. This member; also known as aldehyde reductase; is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist; all encoding the same protein.
• Synonyms: ALDR1; ALR; ARM; DD3; HEL-S-6

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways