STEAP4 Rabbit Polyclonal Antibody

CAT#: TA324150

Anti-STEAP4 Rabbit Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: HepG2 cell lysate
  IHC: 40-200
  Positive control: Human liver cancer
  Predicted cell location: Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 441-456 amino acids of human STEAP family member 4
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: STEAP4 metalloreductase
• Database Link:
  NP_078912
  Entrez Gene 117167 MouseEntrez Gene 499991 RatEntrez Gene 79689 Human
  UniProt ID Q687X5
• Background: The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family; and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+); using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism; and may contribute to the normal biology of the prostate cell; as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: STAMP2; TIARP; TNFAIP9

Reference Data

• Protein Families: Druggable Genome, Transmembrane