ADAM2 Rabbit Polyclonal Antibody

CAT#: TA324288

Anti-ADAM2 Rabbit Polyclonal Antibody

Product Images

Predicted band size: 64 kDa. Positive control: 293T and hela cell lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lane 1: 293T cell lysate Lane 2: Hela cell lysate Lysates: 40 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 15 seconds)

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  Predicted cell location: Cytoplasm. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using ADAM2 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification:x200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1:1000-2000, WB: 1:200-1000, IHC: 1:25-100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to C terminal 250 amino acids of human ADAM metallopeptidase domain 2
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 64 kDa
• Gene Name: ADAM metallopeptidase domain 2
• Database Link:
  NP_001455
  Entrez Gene 11495 MouseEntrez Gene 56806 RatEntrez Gene 2515 Human
  UniProt ID Q99965
• Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.
• Synonyms: CRYN1; CRYN2; CT15; FTNB; PH-30b; PH30; PH30-beta

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane