ATF2 Rabbit Polyclonal Antibody

CAT#: TA325235

Rabbit Polyclonal ATF2 (Ser62 or 44) Antibody (Phospho-specific)

Product Images

Western blot analysis of ATF2 phosphorylation expression in TNF-a treated HeLa whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IP
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human ATF2 around the phosphorylation site of Serine 62 or 44
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 52 kDa
• Gene Name: activating transcription factor 2
• Database Link:
  NP_001243019
  Entrez Gene 11909 MouseEntrez Gene 81647 RatEntrez Gene 1386 Human
  UniProt ID P15336
• Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro
• Synonyms: CRE-BP1; CREB-2; CREB2; HB16; TREB7

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: MAPK signaling pathway