DDIT3 Rabbit Polyclonal Antibody

CAT#: TA325409

Rabbit Polyclonal CHOP (Ser30) Antibody (Phospho-specific)

Product Images

Western blot analysis of CHOP phosphorylation expression in PMA treated Jurkat whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IF/ICC: 1:100-1:500
• Reactivities: Human, Mouse
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human CHOP around the phosphorylation site of Serine 30
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 19 kDa
• Gene Name: DNA damage inducible transcript 3
• Database Link:
  NP_001181982
  Entrez Gene 13198 MouseEntrez Gene 1649 Human
  UniProt ID P35638
• Background: CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity.
• Synonyms: CEBPZ; CHOP; CHOP-10; CHOP10; GADD153

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: MAPK signaling pathway