CRMP2 (DPYSL2) Rabbit Polyclonal Antibody

CAT#: TA325419

Rabbit Polyclonal DRP-2 (Thr514) Antibody (Phospho-specific)

Product Images

Western blot analysis of DRP-2 phosphorylation expression in PMA treated NIH-3T3 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IF/ICC: 1:100-1:500
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human DRP-2 around the phosphorylation site of Threonine 514
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 65/70 kDa
• Gene Name: dihydropyrimidinase like 2
• Database Link:
  NP_001184222
  Entrez Gene 12934 MouseEntrez Gene 25416 RatEntrez Gene 1808 Human
  UniProt ID Q16555
• Background: CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.
• Synonyms: CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Axon guidance