JAK1 Rabbit Polyclonal Antibody

CAT#: TA325582

Rabbit Polyclonal JAK1 (Tyr1022) Antibody (Phospho-specific)

Product Images

Western blot analysis of JAK1 phosphorylation expression in A549 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human JAK1 around the phosphorylation site of Tyrosine 1022
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 130 kDa
• Gene Name: Janus kinase 1
• Database Link:
  NP_002218
  Entrez Gene 16451 MouseEntrez Gene 84598 RatEntrez Gene 3716 Human
  UniProt ID P23458
• Background: Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain.
• Synonyms: JAK1A; JAK1B; JTK3

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer