gamma Catenin (JUP) Rabbit Polyclonal Antibody

CAT#: TA325603

Rabbit Polyclonal Catenin-gamma Antibody

Product Images

Western blot analysis on HeLa cell lysate using Catenin-gamma Antibody

• 

  Immunohistochemical analysis of paraffin-embedded breast carcinoma tissue using Catenin-? Antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against a synthesized A synthesized peptide derived from human Catenin-gamma.
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: junction plakoglobin
• Database Link:
  NP_002221
  Entrez Gene 16480 MouseEntrez Gene 81679 RatEntrez Gene 3728 Human
  UniProt ID P14923
• Background: desmoplakin 3 Common junctional plaque protein. The membrane- associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Belongs to the beta-catenin family. Homodimer. Interacts with MUC1.
• Synonyms: ARVD12; CTNNG; DP3; DPIII; PDGB; PKGB

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer