LCK Rabbit Polyclonal Antibody

CAT#: TA325617

Rabbit Polyclonal Lck (Tyr505) Antibody (Phospho-specific)

Product Images

Western blot analysis of Lck phosphorylation expression in Jurkat whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human Lck around the phosphorylation site of Tyrosine 505
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 56 kDa
• Gene Name: LCK proto-oncogene, Src family tyrosine kinase
• Database Link:
  NP_001036236
  Entrez Gene 16818 MouseEntrez Gene 313050 RatEntrez Gene 3932 Human
  UniProt ID P06239
• Background: Tyrosine kinase that plays an essential role for the selection and maturation of developing t-cell in the thymus and in mature t-cell function.
• Synonyms: IMD22; LSK; p56lck; pp58lck; YT16

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Stem cell - Pluripotency
• Protein Pathways: Natural killer cell mediated cytotoxicity, Primary immunodeficiency, T cell receptor signaling pathway