Tau (MAPT) Rabbit Polyclonal Antibody

CAT#: TA325673

Rabbit Polyclonal Tau (Ser422) Antibody (Phospho-specific)

Product Images

Western blot analysis of Tau phosphorylation expression in Mouse braintissue lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human Tau around the phosphorylation site of Serine 422
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 80 kDa
• Gene Name: microtubule associated protein tau
• Database Link:
  NP_001116538
  Entrez Gene 17762 MouseEntrez Gene 29477 RatEntrez Gene 4137 Human
  UniProt ID P10636
• Background: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type.
• Synonyms: DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, MAPK signaling pathway