STAT6 Rabbit Polyclonal Antibody

CAT#: TA325908

Rabbit Polyclonal STAT6 (Thr645) Antibody (Phospho-specific)

Product Images

Western blot analysis of STAT6 phosphorylation expression in IL-4 treated HeLa whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IP
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human STAT6 around the phosphorylation site of Threonine 645
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 94 kDa
• Gene Name: signal transducer and activator of transcription 6
• Database Link:
  NP_001171549
  Entrez Gene 20852 MouseEntrez Gene 362896 RatEntrez Gene 6778 Human
  UniProt ID P42226
• Background: STAT6 transcription factor of the STAT family. Plays a central role in IL4-mediated biological responses. Induces the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4.
• Synonyms: D12S1644; IL-4-STAT; STAT6B; STAT6C

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
• Protein Pathways: Jak-STAT signaling pathway