TIMP2 Rabbit Polyclonal Antibody

CAT#: TA325939

Rabbit Polyclonal TIMP2 Antibody

Product Images

Western blot analysis of TIMP2 expression in A549 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IF/ICC: 1:100-1:500
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human TIMP2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 24 kDa
• Gene Name: TIMP metallopeptidase inhibitor 2
• Database Link:
  NP_003246
  Entrez Gene 21858 MouseEntrez Gene 29543 RatEntrez Gene 7077 Human
  UniProt ID P16035
• Background: TIMP2 Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
• Synonyms: CSC-21K; DDC8

Reference Data

• Protein Families: Druggable Genome, Secreted Protein