WNK1 Rabbit Polyclonal Antibody

CAT#: TA325977

Rabbit Polyclonal WNK1 (Thr58) Antibody (Phospho-specific)

Product Images

Western blot analysis of WNK1 phosphorylation expression in EGF treated 293 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human WNK1 around the phosphorylation site of Threonine 58
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 230 kDa
• Gene Name: WNK lysine deficient protein kinase 1
• Database Link:
  NP_001171914
  Entrez Gene 116477 RatEntrez Gene 232341 MouseEntrez Gene 65125 Human
  UniProt ID Q9H4A3
• Background: WNK1 a serine-threonine protein kinase that controls sodium and chloride ion transport. May regulate the activity of the thiazide-sensitive Na-Cl cotransporter SLC12A3 by phosphorylation. May also play a role in actin cytoskeletal reorganization.
• Synonyms: HSAN2; HSN2; KDP; p65; PPP1R167; PRKWNK1; PSK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase