GJA1 Rabbit Polyclonal Antibody

CAT#: TA325991

Rabbit Polyclonal Connexin 43 Antibody

Product Images

Western blot analysis on HuvEc cell lysate using Connexin 43 Antibody

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  Immunohistochemical analysis of paraffin- embedded ?human brain tissue using Connexin 43 Antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:100-1:500
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against a synthesized A synthesized peptide derived from human Connexin 43.
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: gap junction protein alpha 1
• Database Link:
  NP_000156
  Entrez Gene 14609 MouseEntrez Gene 24392 RatEntrez Gene 2697 Human
  UniProt ID P17302
• Background: Cx43 an integral membrane protein of the connexin family, alpha-type (group II) subfamily. Hexamers of connexin-43 form connexons, which aggregate together to form gap junctions, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.
• Synonyms: AVSD3; CMDR; CX43; EKVP; GJAL; HLHS1; HSS; ODDD; PPKCA

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Gap junction