GRIA1 Rabbit Polyclonal Antibody

CAT#: TA325994

Rabbit Polyclonal GluR1 (Ser863) Antibody (Phospho-specific)

Product Images

Western blot analysis of GluR1 phosphorylation expression in PMA treated HeLa whole cell lysates, The lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against A synthesized peptide derived from human GluR1 around the phosphorylation site of Serine 863
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 102 kDa
• Gene Name: glutamate ionotropic receptor AMPA type subunit 1
• Database Link:
  NP_000818
  Entrez Gene 14799 MouseEntrez Gene 50592 RatEntrez Gene 2890 Human
  UniProt ID P42261
• Background: GluR1 an integral membrane protein belonging to the glutamate-gated ion channel family. L-glutamate (Glu) acts as an excitatory neurotransmitter at many synapses in the central nervous system.
• Synonyms: GluA1; GLUH1; GLUR1; GLURA; HBGR1

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction