RSK1 p90 (RPS6KA1) Rabbit Polyclonal Antibody [Clone ID: N/A]

CAT#: TA326338

Rabbit polyclonal p90 RSK1 Antibody

Product Images

Western blot analysis of P90 RSK1 immuno-precipitated from the mouse brain extract (right) and using RSK1-HRP as a probe. Immuno-precipitated negative control (left).

Specifications

Product Data

• Clone Name: N/A
• Applications: WB
• Recommended Dilution: WB: 1ug/ml
• Reactivities: Bovine, Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Human p90 RSK1 C-terminal peptide, conjugated to KLH
• Formulation: TBS, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: ribosomal protein S6 kinase A1
• Database Link:
  NP_002944
  Entrez Gene 20111 MouseEntrez Gene 81771 RatEntrez Gene 6195 Human
  UniProt ID Q15418
• Background: The p90 ribosomal S6 kinase (Rsk) family comprises four mammalian serine/threonine kinases (Rsk14). In the past, S6K1 and S6K2 were thought to be the predominant operating S6 kinases, however RSK 1 and 2 have been shown to phosphorylate S6 in response to the ERK pathway, or otherwise known as the extra cellular signal-regulated kinases pathway. RSK 1 in particular is very multifunctional as it participates in nuclear signaling, regulates nuclear factors, regulates several transcription factors like c-Fos, and interacts with the transcriptional coactivator CREB-binding protein. As a result, RSK1 seems to have an important role in cellular growth control and proliferation. .
• Synonyms: HU-1; MAPKAPK1A; p90Rsk; RSK; RSK1
• Note: Detects a ~90kDa protein corresponding to the molecular mass of p90 RSK1 on SDS PAGE immunoblots.

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Long-term potentiation, MAPK signaling pathway, mTOR signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation