Synaptophysin (SYP) Mouse Monoclonal Antibody [Clone ID: EP10]

CAT#: TA326339

Mouse monoclonal Synaptophysin (native) Antibody

Product Images

IHC analysis of Synaptophysin using the antibody

• 

  IHC analysis of Synaptophysin using the antibody

Specifications

Product Data

• Clone Name: EP10
• Applications: IHC
• Recommended Dilution: WB: 1.0ug/ml
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Immunoprecipitate of human brain
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Purification: Protein G Purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: synaptophysin
• Database Link:
  NP_003170
  Entrez Gene 6855 Human
• Background: Synaptophysin is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa . It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for the presynaptic vesicle, and functions in synaptic vesicle exocytois, including cholesterol-dependent vesicle biogeneis, regulation of SNARE assembly via interaction with VAMP/synaptobrevin, formation of the fusion pore initiating neurotransmitter release, and activation of vesicle endocytosis . This gene has also been implicated in X linked mental retardation .
• Synonyms: MRX96; MRXSYP
• Note: Detects ~38kDa.

Reference Data

• Protein Families: Secreted Protein, Transmembrane