VAMP1 Mouse Monoclonal Antibody [Clone ID: SP-11]

CAT#: TA326386

Mouse monoclonal VAMP1/2 Antibody

Product Images

Western blot analysis of VAMP1/2 in rat brain tissues, using a 1:1000 dilution of the antibody

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  IHC analysis of VAMP1/2 using the antibody

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  IHC analysis of VAMP1/2 using the antibody

Specifications

Product Data

• Clone Name: SP-11
• Applications: IHC, WB
• Recommended Dilution: WB: 0.5-1ug/ml
• Reactivities: Human. Not yet tested in other species
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Crude human synaptic immunoprecipitate
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Purification: Protein G Purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: vesicle associated membrane protein 1
• Database Link:
  NP_954740
  Entrez Gene 6843 Human
• Background: VAMP-1, also known as vesicle-associated membrane protein, is an 18kDa member of the synaptobrevin family of proteins. It is expressed in neurons, neutrophils, and skeletal muscle cells, and participates in vesicle fusion with the plasma membrane . Synaptobrevins, Syntakins and the 25kDa synaptosomal associated SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane . VAMP-1 is also one of the key proteins in the SNARE complex which is involved in regulated exocytosis .
• Synonyms: SPAX1; SYB1; VAMP-1
• Note: Recognizes the human synaptic vesicle protein syanptobrevin, VAMP, Recognizes VAMP 1 and 2

Reference Data

• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: SNARE interactions in vesicular transport