Hsp75 (TRAP1) Mouse Monoclonal Antibody [Clone ID: Trap1-6]

CAT#: TA326389

Mouse monoclonal Trap1 Antibody

Product Images

Western blot analysis of TRAP1 in heat shocked HeLa cells, using a 1:1000 dilution of TA326389.

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  Localization of TRAP1 to motochondria in PC-3-M cells by fluorescence microscopy. A: staining of mitochondria with MitoTracker dye; B: staining of nuclei with DAPI; C: immunofluorescence using a monoclonal antibody to TRAP1 (TA326389);D: tricolor composit

Specifications

Product Data

• Clone Name: Trap1-6
• Applications: IF, WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human. Other species not yet tested
• Host: Mouse
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Immunogen: Purified recombinant TRAP1
• Formulation: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: TNF receptor associated protein 1
• Database Link:
  NP_057376
  Entrez Gene 10131 Human
  UniProt ID Q12931
• Background: The 90 kDa heat shock protein (hsp90) family of proteins that play an important physiological role. Hsp90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of hsp90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like hsp90, TRAP1 is found to be associated with numerous proteins involved in diverse actions . Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. Thisobservation and the fact that TRAP1 is shown to have a mitochondrial targeting presequence strongly implicates TRAP1 as a mitochondrial matrix protein .
• Synonyms: HSP 75; HSP75; HSP90L; TRAP-1
• Note: Detects Trap1. Detects ~75kDa.

Reference Data

• Protein Families: Druggable Genome