SNAP25 Mouse Monoclonal Antibody [Clone ID: SP-12]

CAT#: TA326406

Mouse monoclonal SNAP-25 Antibody

Product Images

Western blot analysis of SNAP25 in a human cell line mix using a 1:1000 dilution of the antibody

Specifications

Product Data

• Clone Name: SP-12
• Applications: WB
• Recommended Dilution: WB: 1:1000, ICC/IF: 1:1000, ELISA: 1:5000
• Reactivities: Feline, Human, Mouse, Rat, Pig
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Raised against a crude synaptic preparation from the post mortem human brain
• Formulation: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: synaptosome associated protein 25kDa
• Database Link:
  NP_570824
  Entrez Gene 20614 MouseEntrez Gene 25012 RatEntrez Gene 6616 Human
• Background: Synaptosomal-associated protein 25 (SNAP-25) is a membrane bound protein anchored to the cytosolic face of membrane via palmitoyl side chains in the middle of the molecule . It is a component of the SNARE complex, which is proposed to account for the specificity of membrane fusion and to directly execute fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together . SNAP25 exists as two alternatively spliced isoforms, SMAP25A and SNAP25B. These isoforms are differentially expressed in neurons and neuroendocrine cells and they differ by 9 amino acids in the central portion of the protein .
• Synonyms: bA416N4.2; dJ1068F16.2; RIC-4; RIC4; SEC9; SNAP; SNAP-25
• Note: ~29kDa

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: SNARE interactions in vesicular transport