Bim (BCL2L11) Rabbit Polyclonal Antibody [Clone ID: N/A]

CAT#: TA326413

Rabbit polyclonal BIM/BOD (IN2) Antibody


USD 410.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Clone Name N/A
Applications IF, WB
Recommended Dilution WB: 1:400, ICC: 1:100
Reactivities Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Internal central amino acids of human Bim
Formulation PBS with 0.02% sodium azide
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name BCL2 like 11
Background Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bim/BOD is a group of three splice variants, BimEL, BimL and BimS, with apparent molecular masses of ~23, 16, and 13 kDa, respectively. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat . Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines .
Synonyms BAM; BIM; BOD
Note Detects a 23kDa protein corresponding to the molecular mass of Bim on SDS PAGE immunoblots.
Reference Data
Protein Families Druggable Genome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.