alpha 2C Adrenergic Receptor (ADRA2C) Mouse Monoclonal Antibody [Clone ID: S330A-80]

CAT#: TA326436

Mouse monoclonal Alpha-2C Adrenergic Receptor Antibody

Specifications

Product Data

• Clone Name: S330A-80
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor
• Formulation: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adrenoceptor alpha 2C
• Database Link:
  NP_000674
  Entrez Gene 11553 MouseEntrez Gene 152 Human
  UniProt ID P18825
• Background: The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.
• Synonyms: ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR
• Note: Detects 50kDa or larger (possibly due to dimerization). Does not cross-react with other adrenergic receptors.

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction