Dicer (DICER1) Mouse Monoclonal Antibody [Clone ID: S167-7]

CAT#: TA326471

Mouse Monoclonal Anti-Dicer Antibody

Specifications

Product Data

• Clone Name: S167-7
• Recommended Dilution: WB: 1ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer
• Formulation: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: dicer 1, ribonuclease III
• Database Link:
  NP_001258211
  Entrez Gene 192119 MouseEntrez Gene 299284 RatEntrez Gene 23405 Human
  UniProt ID Q9UPY3
• Background: Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) . After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha , pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs . The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3 UTR of the target mRNA .
• Synonyms: DCR1; Dicer; Dicer1e; HERNA; K12H4.8-LIKE; MNG1; RMSE2
• Note: Detects ~215kDa.

Reference Data

• Protein Families: Druggable Genome