ING1 Rabbit Polyclonal Antibody

CAT#: TA326481

Rabbit Polyclonal Anti-p33 ING1 Antibody

Product Images

Western blot analysis of p33 ING1 in mouse brain extract using the antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1ug/ml
• Reactivities: Human and Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Mouse p33 ING1 N-terminal peptide –KLH conjugates
• Formulation: TBS, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: inhibitor of growth family member 1
• Database Link:
  NP_937862
  Entrez Gene 26356 MouseEntrez Gene 3621 Human
  UniProt ID Q9UK53
• Background: The p33ING1 protein encodes a 33-kD, 294-amino acid protein that displays the characteristics of a tumor suppressor gene. The p33ING1 protein is a regulator of cell cycle, senescence, and apoptosis. It can mediate growth arrest, anchor dependent growth and influence chemosensitivity . It also has a proposed role as a growth regulator, which is consistent with its location in the nucleus . It has been demonstrated that the ING1 gene has three exons and that four mRNA variants are transcribed from three different promoter regions (p33 ING1, p24 ING1, p27 ING1, p47 IG1) . ING1 can possibly influence the above biological functions depending on which variant is expressed .
• Synonyms: p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a
• Note: Detects a ~33kDa protein corresponding to the molecular mass of p33 ING1 on SDS PAGE immunoblots.

Reference Data

• Protein Families: Druggable Genome, Transcription Factors