MDC1 Mouse Monoclonal Antibody [Clone ID: P2B11]

CAT#: TA326493

Mouse Monoclonal Anti-MDC1 Antibody

Specifications

Product Data

• Clone Name: P2B11
• Recommended Dilution: WB: 1:2000
• Reactivities: Bovine, Chimpanzee, Human, Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: GST-tagged recombinant protein corresponding to mouse MDC1 ar and around the N-terminus
• Formulation: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: mediator of DNA damage checkpoint 1
• Database Link:
  NP_055456
  Entrez Gene 240087 MouseEntrez Gene 9656 Human
  UniProt ID Q14676
• Background: MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
• Synonyms: NFBD1
• Note: Detects ~184kDa. This antibody recognizes MDC1 at and around the N-terminus.