Piccolo (PCLO) Mouse Monoclonal Antibody [Clone ID: 6H9-B6]

CAT#: TA326497

Mouse Monoclonal Anti-Piccolo Antibody

Product Images

WB analysis of PCLO using the antibody.

Specifications

Product Data

• Clone Name: 6H9-B6
• Applications: WB
• Recommended Dilution: WB: 1:2000
• Reactivities: Human, Rat. Other species not yet tested
• Host: Mouse
• Isotype: IgG2b, kappa
• Clonality: Monoclonal
• Immunogen: Full length protein
• Formulation: PBS pH7.4, 50% glycerol, 0.09% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: piccolo presynaptic cytomatrix protein
• Database Link:
  NP_149015
  Entrez Gene 56768 RatEntrez Gene 27445 Human
  UniProt ID Q9Y6V0
• Background: Piccolo, also referred to as Aczonin, is a large protein which consists of an N-terminal Zn2+ finger, several piccolo-bassoon homology domains and C-terminal PDZ and C2 domains . In general it is found together with bassoon, a related huge multi-domain protein of the CAZ (cytoskeletal matric assembled at active zones) . Piccolo is a scaffolding protein for proteins involved in endo- and exocytosis of synaptic vesicles. Piccolo has also been shown to interfere with clathrin medicated endocytosis by binding to the F-actin and dynamin binding protein Abp1 .
• Synonyms: ACZ
• Note: No cross-reactivity to Bassoon, band at ~550kDa corresponding to the molecular weight of Piccolo.