Aqp4 Rabbit Polyclonal Antibody

CAT#: TA326513

Rabbit Polyclonal Anti-Aquaporin 4 Antibody


USD 410.00

5 Days*

Size
    • 100 ul

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Specifications

Product Data
Applications IF, WB
Recommended Dilution WB 1:1000-4000, IF: 1:400
Reactivities Human, Mouse, Rat. Not yet tested on other species
Host Rabbit
Clonality Polyclonal
Immunogen C-terminal peptide
Formulation PBS pH7.4, 50% glycerol and 0.09% sodium azide
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name aquaporin 4
Background Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins .Aquaporin 4 is constitutively expressed in the basolateral cell membrane of princinpal collecting duct cells in the kidney and provide a pathway for water to exit these cells . It is also expressed in astrocytes and is upregulated by direct insult to the CNS . Aquaporin 4 has been propsed as the primary autoimmune target in neuromyelitis optica .
Synonyms AQP-4; aquaporin-4; HMIWC2; MGC22454; MIWC; WCH4
Note Detects ~35kDa. May detect larger glycosylated bands ~50kDa.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.