Gria1 Mouse Monoclonal Antibody [Clone ID: S355-1]

CAT#: TA326534

Mouse Monoclonal Anti-GluA1/GluR1 Glutamate Receptor Antibody

Specifications

Product Data

• Clone Name: S355-1
• Recommended Dilution: WB: 1:1000
• Reactivities: Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1
• Formulation: PBS pH7.4, 50% glycerol, 0.1% sodium azide
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: glutamate ionotropic receptor AMPA type subunit 1
• Database Link:
  NP_113796
  Entrez Gene 14799 MouseEntrez Gene 50592 Rat
  UniProt ID P19490
• Background: Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists . GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration .
• Synonyms: GluA1; GLUH1; GluR-A; gluR-A; GLUR1; GLURA; GluRA; HBGR1; HIPA1
• Note: Detects ~100kDa. Does not cross-react with GluR2.