Kcna1 Mouse Monoclonal Antibody [Clone ID: S20-78]

CAT#: TA326548

Mouse Monoclonal Anti-Kv1.1 Antibody

Product Images

IHC analysis of Kv1.1 using the antibody

Specifications

Product Data

• Clone Name: S20-78
• Applications: IHC
• Recommended Dilution: WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide amino acids 458-476 (cytoplasmic C-terminus) of rat Kv1.1 (EEDMNNSIAHYRQANIRTG)
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: potassium voltage-gated channel subfamily A member 1
• Database Link:
  NP_775118
  Entrez Gene 3736 HumanEntrez Gene 16485 MouseEntrez Gene 24520 Rat
  UniProt ID P10499
• Background: Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium channel that in humans is encoded by the SCNA1 gene . It is strongly expressed in a variety of neurons in adult rodents, and it appears to be involved in regulating neuronal excitability. Specifically it plays a role in several developmental processes including proliferation, migration and cell-cell adhesion . The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel .
• Synonyms: AEMK; EA1; HBK1; HUK1; HUKI; Kv1.1; MBK1; MGC126782; MGC138385; MK1; RBK1
• Note: ~85kDa (major: Mature glycosylation), ~65kDa (minor: immature glycosylation)