Mmp9 Mouse Monoclonal Antibody [Clone ID: S51-82]

CAT#: TA326571

Mouse Monoclonal Anti-MMP9 Antibody

Specifications

Product Data

• Clone Name: S51-82
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 1-708 (full length) of rat MMP9
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: matrix metallopeptidase 9
• Database Link:
  NP_112317
  Entrez Gene 4318 HumanEntrez Gene 17395 MouseEntrez Gene 81687 Rat
  UniProt ID P50282
• Background: MMP9, otherwise known as matrix metalloproteinase 9, is involved in the breakdown of extracellular matrix innormal physiological processes such as embryonic development, reproduction and tissue remodeling, aswell as in disease processes like arthritis and metastasis .Among the family members, MMP-2, MMP-3, MMP-7 and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis . MMP activity correlates with cancer development . One mechanism of MMP regulation is transcriptional . Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full length protein .
• Synonyms: CLG4B; GELB; MANDP2; MMP-9
• Note: Detecs ~92kDa and ~82kDa (pro and active forms)