Slc14a2 Rabbit Polyclonal Antibody

CAT#: TA326589

Rabbit Polyclonal Anti-UT-A1 Antibody

Product Images

Western blot analysis of UT-A1 in rat inner medulla using a 1:1000 dilution of the antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: AA911-929 of the rat sequence
• Formulation: PBS, 50% glycerol and 0.09% sodium azide
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: solute carrier family 14 member 2
• Database Link:
  NP_062220
  Entrez Gene 27411 MouseEntrez Gene 54302 Rat
  UniProt ID Q62668
• Background: UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promotor and expressed in the thin descending limb of Henle, viz. UT-A2.)
• Synonyms: FLJ16167; hUT-A6; HUT2; MGC119566; MGC119567; UT-A2; UT2; UTA; UTR
• Note: Detects ~97 and 127kDa.