Slc17a7 Mouse Monoclonal Antibody [Clone ID: S28/9]

CAT#: TA326591

Mouse Monoclonal Anti-VGlut1 Antibody

Product Images

Western blot analysis of VGlut1 on rat membrane tissues using a 1:1000 dilution of the antibody

Specifications

Product Data

• Clone Name: S28/9
• Applications: WB
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Purification: Protein G Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: solute carrier family 17 member 7
• Database Link:
  NP_446311
  Entrez Gene 57030 HumanEntrez Gene 72961 MouseEntrez Gene 116638 Rat
  UniProt ID Q62634
• Background: VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesiclesfrom the brain, exhibiting a conductance for chloride that is blocked by glutamate . Vesicular glutamatetransport has a substantially lower apparent affinity than the plasma membrane excitatory amino acidtransporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in thesame range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognizeboth aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate .
• Synonyms: BNPI; VGLUT1
• Note: Detects ~52kDa. No cross-reactivity against VGlut2.