SAE1 Rabbit Polyclonal Antibody

CAT#: TA326603

Rabbit Polyclonal SAE1 Antibody

Product Images

Western blot analysis of SAE1 in SK-N-SH lysate with SAE1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SAE1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human SAE1.
• Formulation: SAE1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SAE1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SUMO1 activating enzyme subunit 1
• Database Link:
  NP_005491
  Entrez Gene 56459 MouseEntrez Gene 308384 RatEntrez Gene 10055 Human
  UniProt ID Q9UBE0
• Background: SAE1 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (SUMO-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. This sumoylation is effected by the heterodimeric enzyme SAE1/SAE2 and the SUMO-1-conjugating enzyme Ubch9. The sumoylation pathway mediated by SAE1/SAE2 is distinct from other ubiquitin-like protein (Ubl) pathways.
• Synonyms: AOS1; HSPC140; SUA1; UBLE1A

Reference Data

• Protein Pathways: Ubiquitin mediated proteolysis