Sumo 2 (SUMO2) Rabbit Polyclonal Antibody

CAT#: TA326604

Rabbit Polyclonal SUMO2/3 Antibody

Product Images

Western blot analysis of SUMO3 in rat liver tissue lysate with SUMO3 antibody at (A) and (B) 2 ug/mL.

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  Immunohistochemistry of SUMO2/3 in rat liver tissue with SUMO2/3 antibody at 5 ug/mL.

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  Immunofluorescence of SUMO2/3 in rat liver tissue with SUMO2/3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SUMO2/3 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SUMO2.
• Formulation: SUMO2/3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SUMO2/3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: small ubiquitin-like modifier 2
• Database Link:
  NP_008868
  Entrez Gene 170930 MouseEntrez Gene 690244 RatEntrez Gene 6613 Human
  UniProt ID P61956
• Background: SUMO2/3 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (Sumo-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, which is a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. All SUMO proteins localize to the nucleus and are covalently conjugated, affecting protein structure, function and interactions. SUMO2 and 3 are 96% identical and are more mobile within nucleus relative to SUMO1. Specific functional differences between SUMO1 and SUMO2 and 3 remain to be identified.
• Synonyms: HSMT3; Smt3A; SMT3B; SMT3H2; SUMO3

Reference Data

• Protein Families: Druggable Genome