HE4 (WFDC2) Rabbit Polyclonal Antibody

CAT#: TA326648

Rabbit Polyclonal WFDC2 Antibody

Product Images

Western blot analysis of WFDC2 in A549 cell lysate with WFDC2 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of WFDC2 in human lung tissue with WFDC2 antibody at 2.5 ug/mL.

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  Immunofluorescence of WFDC2 in human lung tissue with WFDC2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: WFDC2 antibody was raised against a 16 amino acid peptide near the amino terminus of human WFDC2
• Formulation: WFDC2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: WFDC2 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 14 kDa; Observed: 20 kDa
• Gene Name: WAP four-disulfide core domain 2
• Database Link:
  NP_006094
  Entrez Gene 10406 Human
  UniProt ID Q14508
• Background: The WAP four-disulfide core domain protein 2 (WFDC2), also known as epididymal protein 4, is a member of the WFDC domain family, a family of proteins that is characterized by the presence of Whey Acidic Protein (WAP) domain, and is highly expressed in the lung and salivary gland (1,2). Members of this family include SLPI and elafin, antiproteinases involved in the innate immune system (2). WFDC2 has been proposed to play a critical role in tumor formation and growth in ovarian cancer cells through the regulation of growth- and apoptosis-associated genes and may thus be a potential therapeutic target for epithelial ovarian cancer (3).
• Synonyms: dJ461P17.6; EDDM4; HE4; WAP5

Reference Data

• Protein Families: Secreted Protein, Transmembrane