CD272 (BTLA) Rabbit Polyclonal Antibody

CAT#: TA326653

Rabbit Polyclonal BTLA Antibody

Product Images

Western blot analysis of BTLA in Jurkat cell lysate at (A) 1 and (B) 2 ug/ml.

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  Immunohistochemistry of BTLA in human small intestine tissue with BTLA antibody at 2.5 ug/mL.

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  Immunofluorescence of BTLA in human small intestine tissue with BTLA antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: BTLA antibody was raised against a 17 amino acid peptide near the center of human BTLA.
• Formulation: BTLA Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: BTLA Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 32 kDa; Observed: 40 kDa
• Gene Name: B and T lymphocyte associated
• Database Link:
  NP_861445
  Entrez Gene 151888 Human
  UniProt ID Q7Z6A9
• Background: The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).
• Synonyms: BTLA1; CD272

Reference Data

• Protein Families: Transmembrane