CD160 Rabbit Polyclonal Antibody

CAT#: TA326654

Rabbit Polyclonal CD160 Antibody

Product Images

Western blot analysis of CD160 in K562 cell lysate with CD160 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

• 

  Immunofluorescence of CD160 in Jurkat cells tissue with CD160 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: CD160 antibody was raised against a 17 amino acid peptide near the center of human CD160.
• Formulation: CD160 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: CD160 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 20 kDa; Observed: 25 kDa
• Gene Name: CD160 molecule
• Database Link:
  NP_008984
  Entrez Gene 54215 MouseEntrez Gene 11126 Human
  UniProt ID O95971
• Background: CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain (1). It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1,2). CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells (2,3). Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation (4).
• Synonyms: BY55; NK1; NK28

Reference Data

• Protein Families: Druggable Genome