IL1RL2 Rabbit Polyclonal Antibody

CAT#: TA326663

Rabbit Polyclonal IL-1RL2 Antibody


USD 430.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen IL-1RL2 antibody was raised against a 16 amino acid peptide near the center of human IL-1RL2.
Formulation IL-1RL2 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification IL-1RL2 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size Predicted: 61 kDa; Observed: 55 kDa
Gene Name interleukin 1 receptor like 2
Background IL-1RL2 is a member of the interleukin 1 receptor family, but it is incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity (1). Together with IL-1RAcP, it can bind members of the IL-36 cytokine family, leading to activation of the NF-kappaB pathway (2). IL-1RL2 can also bind to IL-1F10, resulting in a decreased product of Th17 cytokines in response to immunological or LPS challenge, suggesting that one potential role of IL-1RL2 may be to modulate the immune and inflammation response (3).
Synonyms IL-1Rrp2; IL-36R; IL1R-rp2; IL1RRP2
Reference Data
Protein Families Druggable Genome, Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.