IL1F10 Rabbit Polyclonal Antibody

CAT#: TA326664

Rabbit Polyclonal IL-1F10 Antibody

Product Images

Western blot analysis of IL-1F10 in human liver tissue lysate with IL-1F10 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of IL-1F10 in human spleen tissue with IL-1F10 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: IL-1F10 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human IL-1F10.
• Formulation: IL-1F10 antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: IL-1F10 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 17 kDa; Observed: 20 kDa
• Gene Name: interleukin 1 family member 10 (theta)
• Database Link:
  NP_775184
  Entrez Gene 84639 Human
  UniProt ID Q8WWZ1
• Background: The cytokine IL-1 is responsible for initiating a variety of activities through the activation of transcription factors, NF-kappa B and AP-1, thereby promoting host response to injury or infection (1). IL-1F10 (Interleukin-1 family member 10), also known as FIL1T, IL1HY2 or FKSG75, is highly expressed in the skin, spleen and proliferating B-cells of the tonsil (2). IL-1F10 binds soluble IL-1 receptor type 1, and is one of nine Interleukin 1 families clustered on chromosome 2, where it is thought to participate in the regulation of adapted and innate immune responses (3). IL-1F10 and IL-1RN polymorphisms may play an important role in the susceptibility to developing rheumatoid arthritis (4).
• Synonyms: FIL1-theta; FKSG75; IL-1HY2; IL-38; IL1-theta; IL1HY2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein