MAP1LC3A Rabbit Polyclonal Antibody

CAT#: TA326682

Rabbit Polyclonal MAP1LC3A Antibody


USD 430.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen MAP1LC3A antibody was raised against a 10 amino acid peptide near the amino terminus of human MAP1LC3A.
Formulation MAP1LC3A antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification MAP1LC3A antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size Predicted: 147 kDa; Observed: 21 kDa
Gene Name microtubule associated protein 1 light chain 3 alpha
Background Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3A belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3A is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3A, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3).
Synonyms ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.