THAP11 Rabbit Polyclonal Antibody

CAT#: TA326693

Rabbit Polyclonal THAP11 Antibody

Product Images

Western blot analysis of THAP11 in human brain tissue lysate with THAP11 antibody at 1 ug/ml.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: THAP11 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THAP11.
• Formulation: THAP11 antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: THAP11 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 35 kDa; Observed: 38 kDa
• Gene Name: THAP domain containing 11
• Database Link:
  NP_065190
  Entrez Gene 59016 MouseEntrez Gene 307806 RatEntrez Gene 57215 Human
  UniProt ID Q96EK4
• Background: The THAP domain-contining protein 11 (THAP11), also known as Ronin, is an essential factor involved in embryonic stem (ES) cell pluripotency and cell growth (1). THAP 11 contains a THAP domain, a conserved DNA-binding domain common to many proteins associated with chromatin modification and gene expression silencing, and has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases (2). THAP11 can also negatively regulate CD44 v6 expression through its interaction with the poly(rC) binding protein PCBP1 (3).
• Synonyms: CTG-B43a; CTG-B45d; HRIHFB2206; RONIN