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C19orf80 (ANGPTL8) Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | IF, IHC, WB |
| Recommended Dilution | WB: 1 - 2 ug/mL, ICC: 5 ug/mL |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Betatrophin antibody was raised against a 16 amino acid peptide near the amino terminus of human Betatrophin. The immunogen is located within amino acids 40 - 90 of Betatrophin. |
| Formulation | Betatrophin antibody is supplied in PBS containing 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Betatrophin antibody is affinity chromatography purified via peptide column. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | Predicted: 22 kDa; Observed: 22 kDa |
| Gene Name | angiopoietin like 8 |
| Database Link | |
| Background | The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels (1,2). Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis (3). |
| Synonyms | C19orf80; PRO1185; PVPA599; RIFL; TD26 |
| Reference Data | |
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