C Reactive Protein (CRP) Rabbit Polyclonal Antibody

CAT#: TA326781

CRP Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of HepG2 cells and mouse liver tissue, using CRP antibody.

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  Immunofluorescence analysis of HeLa cell using CRP antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:10 - 1:100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CRP
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: C-reactive protein, pentraxin-related
• Database Link:
  NP_000558
  Entrez Gene 12944 MouseEntrez Gene 25419 RatEntrez Gene 1401 Human
  UniProt ID P02741
• Background: Human c-Reactive protein (CRP) was discovered in serum of patients as a nonantibody precipitin of the C-polysaccharide from pneumococci. During acute infection, the amounts of circulating CPR increases 100-1000 fold . Serum CRP values are routinely measured to detect or monitor many human diseases and minor elevations of C-reactive protein are predictive of cardiovascular events in patients with coronary heart disease . CRP promotes host defense, is an efficient activator of the classical C cascade, and shown to be opsonic .The opsonic and C activation activities are responsible for the nonspecific host defense activities providing protection in the preimmune stage of acute infections. Additionally, IL-1 and IL-6 are known to stimulate CRP biosynthesis .
• Synonyms: PTX1

Reference Data

• Protein Families: Secreted Protein