PSME3 Rabbit Polyclonal Antibody

CAT#: TA326811

PSME3 Rabbit Polyclonal Antibody


USD 275.00

3 Weeks*

Size
    • 100 ul

Product Images

Frequently bought together (3)
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Specifications

Product Data
Applications WB
Recommended Dilution WB 1:500 - 1:2000
Reactivities Human, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant protein of human PSME3
Formulation Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 30 kDa
Gene Name proteasome activator subunit 3
Background The 20S proteasome is the major proteolytic enzyme complex involved in intracellular protein degradation. PA700, PA28, and PA200 are three major protein complexes that function as activators of the 20S proteasome. There are three evolutionarily conserved subunits of PA28: PA28a (PSME1), PA28β (PSME2), and PA28? (PSME3) . PA28a and PA28β form a heteroheptameric complex and function by binding to the 20S complex at its opening site(s). The PA28a/β complex is present throughout the cell and participates in MHC class I antigen presentation by promoting the generation of antigenic peptides from foreign proteins. PA28? exists in the form of a homoheptamer and is mainly located in the nucleus. The PA28? complex exerts its function by binding and guiding specific nuclear target proteins to the 20S proteasome for further degradation.
Synonyms HEL-S-283; Ki; PA28-gamma; PA28G; PA28gamma; REG-GAMMA
Reference Data
Protein Families Stem cell - Pluripotency
Protein Pathways Antigen processing and presentation, Proteasome

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.