U2AF35 (U2AF1) Rabbit Polyclonal Antibody

CAT#: TA326899

U2AF1 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of Colon320 cell and Hela cell lysate using U2AF1 antibody.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB: 1:500-1:2000;IHC: 1:50-1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human U2AF1
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: U2 small nuclear RNA auxiliary factor 1
• Database Link:
  NP_006749
  Entrez Gene 108121 MouseEntrez Gene 687575 RatEntrez Gene 7307 Human
  UniProt ID Q01081
• Background: U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.
• Synonyms: FP793; RN; RNU2AF1; U2AF35; U2AFBP

Reference Data

• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Spliceosome