Cullin 3 (CUL3) Rabbit Polyclonal Antibody

CAT#: TA326917

Rabbit anti-CUL3 Polyclonal Antibody

Product Images

Western blot analysis of Jurkat cell lysate using CUL3 antibody.

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  Immunofluorescence analysis of HeLa cell using CUL3 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CUL3
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cullin 3
• Database Link:
  NP_003581
  Entrez Gene 26554 MouseEntrez Gene 301555 RatEntrez Gene 8452 Human
  UniProt ID Q13618
• Background: CUL3 (Cullin-3) is a member of the cullin-based ubiquitin ligase family. By interacting with Hrt1 and BTB domain containing proteins, the complex functions as a CUL3-based E3 ligase to bring specific substrates to ubiquitinylation and degradation. The CUL3 complex has been shown to target many substrates involved in cell cycle progression, transcription, development and differentiation.
• Synonyms: CUL-3; PHA2E

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis