BCL2L2 Rabbit Polyclonal Antibody

CAT#: TA326958

Rabbit anti-BCL2L2 Polyclonal Antibody

Product Images

Western blot analysis of HL-60 cell lysate using BCL2L2 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human BCL2L2
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: BCL2 like 2
• Database Link:
  NP_004041
  Entrez Gene 12050 MouseEntrez Gene 60434 RatEntrez Gene 599 Human
  UniProt ID Q92843
• Background: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene.
• Synonyms: BCL-W; BCL2-L-2; BCLW; PPP1R51

Reference Data

• Protein Families: Druggable Genome, Transmembrane