Carbonic Anhydrase III (CA3) Rabbit Polyclonal Antibody

CAT#: TA327000

CA3 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CA3 antibody.

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  Immunohistochemistry of paraffin-embedded rat testis using CA3 antibody at dilution of 1:200 (200x lens).

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  Immunohistochemistry of paraffin-embedded rat testis using CA3 antibody at dilution of 1:200 (400x lens).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CA3
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: carbonic anhydrase 3
• Database Link:
  NP_005172
  Entrez Gene 761 Human
  UniProt ID P07451
• Background: Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008]
• Synonyms: CAIII; Car3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Nitrogen metabolism