BDNF Rabbit Polyclonal Antibody

CAT#: TA327032

Rabbit anti-BDNF Polyclonal Antibody

Product Images

Western blot analysis of extracts of SH-SY5Y cell and PC-12 cell lines, using BDNF antibody.

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  Immunohistochemistry of paraffin-embedded rat lung using BDNF antibody at dilution of 1:100 (200x lens).

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  Immunohistochemistry of paraffin-embedded human esophagus using BDNF antibody at dilution of 1:100 (200x lens).

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB,1:500 - 1:1000
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 28kDa
• Gene Name: brain-derived neurotrophic factor
• Database Link:
  NP_001700
  Entrez Gene 12064 MouseEntrez Gene 24225 RatEntrez Gene 627 Human
  UniProt ID P23560
• Background: This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
• Synonyms: ANON2; BULN2

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Transmembrane
• Protein Pathways: Huntington's disease, MAPK signaling pathway, Neurotrophin signaling pathway